Kolena AI Agent

Skin-Image Measurement (Vision)

Turn a personal-care study's standardized skin photographs into clean, cited per-image measurements and change vs baseline - wrinkles, spots, pores, redness, texture, radiance, or perceived age - with a capture-quality gate on the front.

Consumer R&D / Personal CareResearch & Insights

Impact

Manual, image-by-image measurement of each study's standardized photographs and re-keying into the master sheet - normally done by hand across many volunteers and timepoints - compressed into a single cited, quality-gated run that emits the change-vs-baseline read-out directly

per study image set

Volume fit

Works best for

R&D and imaging teams processing many-volunteer, multi-timepoint image studies where each study yields dozens to hundreds of standardized photographs to measure

Too small for

a one-off read of a single before/after image pair

Typical inputs

Documents

  • Standardized skin study photographs (one volunteer's measurement area at one timepoint per image)
  • Barcoded image filenames encoding volunteer, timepoint, area, and treatment code
  • Cross-polarized, parallel-polarized, white-light, or UV facial images
  • Any accompanying capture log or study protocol

Systems

  • Facial-imaging system / capture station
  • Contract-lab or imaging portal
  • SharePoint
  • Google Drive

Output

A cited measurement read-out - image inventory with barcode parse, a per-image capture-quality assessment and study-level quality gate, per-image skin-attribute measurements within a defined region of interest, per-volunteer change vs baseline (absolute and percent), a group-level change summary, an overall change call, data-integrity checks, and an analyst summary

Delivered to

  • Efficacy-study data-extraction workflow
  • Claims substantiation dossier / Product Information File
  • R&D study database or tracker

What it extracts

· 10 fields
  • Form

    Study & Imaging Overview

    The one-look roll-up read from the image set - study design, imaging modality and lighting, measurement area, product category, the attribute(s) measured, and the number of volunteers, timepoints, and images - so a reviewer can orient before reading detail.

  • Table

    Image Inventory & Barcode Parse

    Every image with its verbatim filename and the volunteer, timepoint, measurement area, and treatment code parsed from its barcode; a mis-parsed barcode attributes a measurement to the wrong volunteer or timepoint and invalidates the read-out.

  • Table

    Image Quality Assessment

    Each image scored against standardized-capture criteria - lighting consistency, pose/angle alignment, focus, and region-of-interest framing - with an overall Pass / Borderline / Fail call and an issue note, because repeatable capture is the precondition for a trustworthy before/after comparison.

  • Classification

    Study Image-Quality Gate

    The study-level go/no-go on the imagery - all pass, minor issues usable with caveats, some fail and re-capture is recommended, or not analyzable - read from the per-image quality assessment.

  • Table

    Per-Image Skin Attribute Measurements

    The core measurement - one numeric estimate per image and attribute (perceived age by default; also wrinkles/fine lines, spots/pigmentation, pores, redness/erythema, texture, radiance) within a defined region of interest, on a single consistent scale aligned to a grading reference where one exists.

  • Table

    Baseline & Timepoint Comparison

    Each volunteer's change over time per attribute and follow-up timepoint - baseline and timepoint value, absolute change, and percent change vs baseline, with an improvement/worsening direction on the attribute's convention - the effect on the volunteer's own skin.

  • Table

    Group-Level Change Summary

    The panel roll-up per attribute and timepoint - mean baseline, mean timepoint, mean percent change vs baseline, contributing N, and direction of effect - computed only from complete baseline-to-timepoint pairs, never by placing a group mean into an individual's cell.

  • Classification

    Overall Measured Change

    The single descriptive call on the primary attribute - improvement, no meaningful change, mixed across attributes, or insufficient/gated-out imagery - read from the quality gate, per-volunteer comparison, and group summary.

  • Table

    Measurement Data-Integrity Validation

    The consistency checks an analyst runs before trusting the read-out - every image parsed, failed-QC images excluded, a baseline present per volunteer, percent change ties to the values, one scale per attribute, no group mean in an individual cell, and consistent region of interest - each Pass / Fail / Review.

  • Text

    Study Measurement Summary

    The analyst narrative - imaging setup and panel, whether the imagery cleared the quality gate, the key measured changes and their magnitude on the correct basis, the overall change call, and any integrity flags or caveats to resolve before relying on the results.

Prerequisites

  • The full image set for the study (baseline plus follow-up timepoints)
  • The parameter to measure (perceived age is the default; e.g. wrinkles, spots, pores, redness, texture, or radiance)
  • The barcode/filename convention and, if separate, the treatment-code key

Human review

An image-analysis or claims scientist reviews the capture-quality gate, spot-checks per-image measurements against the images, and confirms the change-vs-baseline read-out and improvement conventions before the numbers feed a claim. Statistical significance is established in the downstream efficacy-study workflow, not here.

Where it fits

Cosmetic / personal-care instrumental image measurement for efficacy testing

Volunteers are photographed under standardized conditions - a multi-point-positioned facial-imaging system, controlled lighting (cross-polarized, parallel-polarized, white, or UV) - at baseline and one or more follow-up timepoints; the barcoded image set is delivered by portal, shared drive, or upload

This step

Computer-vision measurement of the skin images and baseline-to-timepoint change

After

Clinical / Efficacy Study Data ExtractionProduct Claims & Concept Development
R&D formulation decisions and go/no-go
Statistical significance testing and claim sign-off

Who uses it

Image Analysis ScientistEfficacy / Clinical Study ManagerR&D Product Development ScientistClaim Substantiation Scientist

Grounded in

  • Regulation (EU) No 655/2013 - common criteria for cosmetic product claimsverified as of 2026-07-22
  • Cosmetics Europe - Guidelines for Cosmetic Product Claim Substantiationverified as of 2026-07-22
  • Standardized facial imaging (VISIA-style, e.g. Canfield) - de-facto method for objective skin-feature measurementverified as of 2026-07-22
  • Validated photonumeric grading scales for skin attributes (e.g. wrinkle-severity and erythema scales)verified as of 2026-07-22

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